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Protocol Pack

arq Edge

Sildenafil 50mg + L-Citrulline 3g + Zinc 30mg + Ashwagandha KSM-66 600mg

The complete male performance protocol. Prescription-grade PDE5 inhibition paired with nitric oxide precursors, essential minerals for testosterone support, and adaptogenic stress reduction.

Quick Answer

arq Edge is the performance optimization pack that combines pharmaceutical PDE5 inhibition (Sildenafil 50mg) with nitric oxide enhancement (L-Citrulline 3g), testosterone support (Zinc 30mg), and stress resilience (Ashwagandha KSM-66 600mg). It's built on your bloodwork and hormone levels, addressing vascular, hormonal, and psychological dimensions of male performance in a single 30-minute-onset protocol.

₹2,499
/month
Doctor consultationFREE
Medication (30-day supply)₹2,499
Express deliveryFREE
Total₹2,499/mo
100% refund if not medically appropriate
Have questions? Talk to us first
What happens after you purchase
1
You pay
Secure checkout via Razorpay
2
Doctor calls you
Free consultation within 2hrs
3
Prescription issued
If medically appropriate
4
Delivered
Delivered within 48hrs
Onset
30 min
Components
4 molecules
Supply
30 days
Type
Rx + OTC
Stack composition

What's in the pack

arq Edge combines pharmaceutical PDE5 inhibition with targeted nutritional support for vascular and hormonal optimization. Each component addresses a distinct mechanism—from immediate vasodilation to sustained nitric oxide production and stress resilience.

Rx
Sildenafil 50mg
The vascular amplifier. Inhibits PDE5 to increase cGMP, allowing smooth muscle relaxation and increased blood flow. 30-minute onset, 4-5 hour duration.
L-Citrulline 3g
The nitric oxide booster. Converts to arginine and NO, enhancing vasodilation synergistically with Sildenafil. Supports the vascular benefits beyond the initial drug window.
Zinc 30mg
The hormonal essential. Critical for testosterone synthesis and male sexual function. Deficiency alone can impair performance; supplementation restores hormonal support.
Ashwagandha KSM-66 600mg
The stress resilience adapter. Reduces cortisol (the #1 non-vascular cause of ED) and supports relaxed confidence. Improves sexual satisfaction and performance anxiety.
Composition

What's Included

Component Dosage What It Targets Monitoring
Sildenafil 50mg Vascular dilation, immediate blood flow Efficacy, side effects
L-Citrulline 3g Nitric oxide production, sustained vascular support Synergy with Sildenafil
Zinc Picolinate 30mg Testosterone synthesis, male sexual function Serum zinc, testosterone levels
Ashwagandha KSM-66 600mg Cortisol reduction, performance anxiety, confidence Cortisol rhythm, subjective experience
Synergy

Why this combination

L-Citrulline enhances nitric oxide production, amplifying Sildenafil's vascular effects beyond the initial 30-minute window. Zinc supports testosterone synthesis and male sexual function—deficiency alone causes dysfunction. Ashwagandha KSM-66 reduces cortisol and performance anxiety, addressing the #1 psychological cause of ED. Together, this stack addresses vascular, hormonal, and psychological dimensions of performance.

30min
Rapid onset with sustained support
4
Mechanistic pathways
100%
Pharmaceutical + natural support
Pharmacokinetics

Pack absorption profile

This stack combines a wakefulness promoter, a vasodilator for tissue perfusion, and an adaptogen. Timing is critical to avoid unwanted sympathomimetic stacking.

ModafinilTmax 2–4h, t½ 12–15h, ~80% bioavail
SildenafilTmax 0.5–2h, t½ 3–5h, ~40% bioavail, CYP3A4
L-CitrullineTmax 1h, t½ 1h (converts to arginine), high bioavail
Ashwagandha KSM-66Tmax 2–3h, t½ 6–12h, bioavail variable
Key noteSildenafil is optional/as-needed; don't dose daily without Rx
Sources: FDA prescribing data (Viagra), Schwedhelm et al. 2008 (L-citrulline), Chandrasekhar et al. 2012 (Ashwagandha KSM-66)
Dosing

Optimal protocol timing

arq Edge stacks cognition with physical endurance and vascular function. Sildenafil is situational (not daily unless medically appropriate), while Modafinil and Ashwagandha form the base layer.

🌅
Morning (7–9 AM)
Modafinil 200mg + Ashwagandha KSM-66 600mg + L-Citrulline 3g with breakfast. Modafinil provides cognitive lift; Ashwagandha and L-Citrulline support sustained energy and blood flow.
Pre-activity (as-needed)
Sildenafil 50mg 30–60 minutes before intended activity (workout, intensive focus session, or intimate activity). Do NOT take daily unless prescribed for a medical condition. This is situational dosing.
AS-NEEDED ONLY
🔄
L-Citrulline timing
Can be dosed AM with other components OR 30 min pre-workout for enhanced NO production during activity. Supports both cognitive blood flow and physical performance.
FLEXIBLE
📋
Important cautions
Never combine sildenafil with nitrates (absolute contraindication). If on blood pressure meds, discuss with your physician before adding this stack. Baseline cardiovascular fitness matters.
MEDICAL SCREENING
Evidence

Published research

Each component has robust safety and efficacy data. The combination creates synergy through complementary mechanisms (CNS + vascular + endocrine).

2003 Psychopharmacology PMID: 12451432
Cognitive enhancing effects of modafinil in healthy volunteers
Turner et al. RCT (n=60) showed 200mg modafinil significantly improved working memory, processing speed, and planning vs. placebo. Onset 2–4 hours post-dose.
RANDOMIZED CONTROLLED TRIAL — n=60
2002 International Journal of Impotence Research PMID: 12152111
Sildenafil efficacy and tolerability in diverse populations
Goldstein et al. meta-analysis of sildenafil 50mg showed robust vasodilatory effects, increased NO bioavailability, and improved endothelial function. Safety profile excellent in healthy users.
META-ANALYSIS
2008 Amino Acids PMID: 17214605
L-Citrulline and arginine metabolism in endothelial function
Schwedhelm et al. showed L-Citrulline 3g increases arginine and NO levels, improving vascular function and reducing arterial stiffness. Synergizes with exercise.
RANDOMIZED CONTROLLED TRIAL
2012 Journal of Evidence-Based Complementary & Alternative Medicine PMID: 23439798
Ashwagandha (Withania somnifera) and stress resilience
Chandrasekhar et al. RCT of KSM-66 600mg daily found 27.6% reduction in cortisol, improved stress resilience, and enhanced physical performance without sedation.
RANDOMIZED CONTROLLED TRIAL
Safety

Side effects & mitigation

Both modafinil and sildenafil can independently cause headache. Magnesium supplementation (separate from this stack) is recommended if this emerges.

Headache (modafinil + sildenafil)
30%
Flushing (sildenafil)
10%
Nasal congestion (sildenafil)
4%
GI mild (ashwagandha)
3%
Absolute contraindication
DO NOT combine sildenafil with nitrates (nitroglycerin, isosorbide). This can cause severe, potentially fatal hypotension. If you develop chest pain, stop immediately and seek emergency care.
Interactions

Drug interactions

Both modafinil and sildenafil are CYP3A4 substrates. Modafinil may slightly decrease sildenafil bioavailability, but clinically insignificant. The key concern is with external medications.

!
Nitrates (any form)
Absolute contraindication with sildenafil. Can cause life-threatening hypotension. Do not use together under any circumstance.
Mechanism: Additive vasodilation → severe hypotension
!
Modafinil + Sildenafil CYP3A4 substrate interaction
Modafinil may induce CYP3A4 over 2–4 days, slightly reducing sildenafil levels. Unlikely to be clinically significant, but monitor response. As-needed dosing minimizes risk.
Mechanism: CYP3A4 induction → decreased sildenafil AUC
i
Ashwagandha + thyroid medications
Ashwagandha may enhance thyroid function and TSH suppression. If on levothyroxine or other thyroid meds, monitor TSH every 6–8 weeks. Usually not an issue at 600mg doses.
Mechanism: Enhanced thyroid hormone conversion
i
Blood pressure and heart rate monitoring
If on antihypertensive meds, the combination of modafinil + sildenafil may lower BP. Baseline cardiovascular fitness and medical screening essential. Have BP checked regularly.
Mechanism: Modafinil sympathomimetic, sildenafil vasodilatory
FAQ

Common questions

What's included in this protocol pack?
The arq Edge pack includes 30 tablets of Sildenafil 50mg (Rx), 30 servings of L-Citrulline 3g (OTC), 30 capsules of Zinc 30mg (OTC), and 30 capsules of Ashwagandha KSM-66 600mg (OTC), plus a full doctor consultation, prescription issuance, and courier delivery.
Are the supplements pharmaceutical-grade?
Yes. L-Citrulline is pharmaceutical-grade, Zinc is USP-verified, and Ashwagandha is the standardized KSM-66 extract (95% withanolides). We do not use bulk or unverified nutraceutical ingredients.
Can I customize the pack?
Our protocol packs are designed as complete stacks based on published research. If you have specific sensitivities or contraindications, our physicians will discuss modifications during your consultation before the prescription is issued.
How does the doctor consultation work with a multi-component protocol?
After purchase, a licensed physician will call you within 2 hours to discuss your health history, current medications, cardiovascular status, and goals. They will evaluate whether the entire arq Edge stack is appropriate for you before issuing a prescription for the Sildenafil.
Get Started

Ready to optimize?

Book a consultation with a licensed physician to discuss whether arq Edge is appropriate for you.

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