Member story
Three years on amlodipine and my BP was still 150/95. arq. found aldosterone 3x normal range. Different medication, BP normalized in 6 weeks.
Your cardiologist reads the full cardiac panel — Lp(a), ApoB, hs-CRP, homocysteine, NT-proBNP — alongside kidney and metabolic markers. The Cardiovascular Protection Protocol is written on your bloodwork, not a ten-minute outpatient reading.
Every panel includes a 15–20 minute video consult with a specialist — read against South Asian-calibrated ranges. The AI works invisibly. The doctor does the medicine.
1 in 4 Indian adults has hypertension. Most are prescribed amlodipine or telmisartan and sent home. No one tests kidney function, aldosterone, cortisol, or insulin resistance — the actual drivers of elevated blood pressure. This means millions are on medication that controls a number without fixing the underlying problem. Hypertension often coexists with diabetes, thyroid dysfunction, and obesity.
These biomarkers reveal the root causes — and what actually works to fix them.
High blood pressure is silent until it's dangerous. 1 in 3 Indian adults has hypertension, and 50% don't know it. But here's what most miss: blood pressure is a symptom, not a diagnosis.
Insulin resistance, high cortisol, kidney dysfunction, and sleep apnea all drive elevated BP. Without testing the root cause, you're treating a number, not a problem.
From optimal to stage 2 hypertension — what each range means and what testing matters.
| Category | BP Range | Risk Level | Lifestyle Changes | Medication? | Key Biomarkers |
|---|---|---|---|---|---|
| Optimal | <120/80 | Healthy | Maintain activity, balanced diet | No | Baseline lipids, kidney function |
| Normal | 120–129/ 80–84 |
Monitor | Increase potassium, reduce sodium | No | Fasting insulin, hsCRP |
| High Normal | 130–139/ 85–89 |
At risk | Aggressive lifestyle optimization | Consider if other risk factors | Insulin, cortisol, eGFR |
| Stage 1 Hypertension |
140–159/ 90–99 |
High | Sleep, stress, exercise essential | Usually yes | Aldosterone, kidney panel, lipids |
| Stage 2 Hypertension |
≥160/≥100 | Critical | Immediate physician guidance | Required + lifestyle | Full metabolic + cardiac markers |
The specific markers that reveal what's driving your blood pressure elevation.
| Biomarker | How It Drives BP | Optimal Range | If Abnormal |
|---|---|---|---|
| Fasting Insulin / HOMA-IR |
High insulin causes sodium retention, vascular stiffness, sympathetic activation | Insulin <10 mIU/L HOMA-IR <2 |
Insulin sensitization via diet, berberine, GLP-1 |
| Morning Cortisol | Chronic stress and elevated cortisol increase BP and vascular tone | 10–20 mcg/dL (8–10 AM) |
Stress management, sleep optimization, adaptogens |
| eGFR / Creatinine / BUN |
Kidney dysfunction impairs sodium regulation and causes hypertension | eGFR >60 mL/min Creatinine 0.7–1.3 mg/dL |
Medication adjustment, nephrology referral if <30 eGFR |
| Aldosterone / Renin Ratio |
Primary aldosteronism (~10% of hypertension) causes sodium retention | Ratio <20–25 (lab-specific) |
Spironolactone or eplerenone if elevated |
| ApoB / Lp(a) | Dyslipidemia accelerates atherosclerosis and hypertension | ApoB <80 mg/dL Lp(a) <30 mg/dL |
Statin if ApoB elevated; manage risk factors |
| hsCRP | Systemic inflammation drives endothelial dysfunction and stiffness | <1.0 mg/L | Anti-inflammatory diet, omega-3, exercise |
| TSH / Free T4 | Hypothyroidism slows metabolism; hyperthyroidism increases heart rate and BP | TSH 0.5–2.0 mIU/L | Levothyroxine if hypothyroid; monitor post-treatment |
| Homocysteine | Elevated homocysteine damages endothelium and increases vascular stiffness | <10 mcmol/L | B vitamins (B6, B12, folate), TMG supplement |
Prevalence of hypertension in India is approximately 1 in 3 adults (32–33%), with nearly 50% unaware of their condition due to lack of systematic screening and detection programs across primary healthcare.
Insulin resistance is present in 40–50% of hypertensive patients and is a key independent driver of elevated blood pressure through mechanisms including sodium retention, increased sympathetic activity, and vascular stiffness.
Primary aldosteronism occurs in 10–12% of unselected hypertensive populations and is a significant, often undiagnosed, secondary cause of hypertension that responds to targeted mineralocorticoid antagonist therapy.
Comprehensive screening for multiple biomarkers (kidney function, aldosterone, cortisol, insulin, lipids, electrolytes) identifies secondary and modifiable causes of hypertension in 20–30% of patients previously thought to have essential hypertension.
Potassium and magnesium supplementation, combined with sodium reduction, can reduce systolic blood pressure by 10–15 mmHg in hypertensive patients — a magnitude comparable to many antihypertensive drugs.
High BP is a symptom, not a disease. Treating only the number while ignoring the root cause is like silencing a smoke alarm instead of extinguishing the fire.
Insulin resistance drives up to 50% of hypertension cases. If your fasting insulin is high, your BP medication won't fix the underlying problem without addressing insulin sensitivity.
Kidney function, electrolytes, and aldosterone matter as much as salt intake. Most Indians don't know their eGFR or aldosterone levels—yet these determine whether your kidneys can regulate BP.
Medication can control BP but won't reverse the underlying cause. Lifestyle optimization + targeted biomarker-driven treatment is the path to either reducing medication or eliminating it entirely.
1 in 3 Indians has hypertension, and 50% don't know it. Silent killer or not, your BP is preventable and reversible — but only if you investigate the cause, not just the number.
Three steps. Your data. Your physician. Your protocol.
100+ biomarkers drawn at your door in 10 minutes. NABL-accredited labs. Results in 5 days. No clinic visit, no waiting rooms — just data.
Your physician reviews kidney function, electrolytes, aldosterone, insulin, and cortisol. Why your BP is high — identified at the root.
Medication adjustment, electrolyte optimisation, insulin sensitisation, or hormonal correction — targeted to your root cause. Delivered in 48h.
No AI chat. No templates. No copy-paste PDFs. A specialist reads your panel against South Asian-calibrated ranges and writes the protocol on a 15–20 minute video consult — inside 7 days of your home draw.